The study of resistance to antifungal agents has lagged behind that of antibacterial resistance for several reasons. Perhaps, fungal diseases were not recognized as important pathogens until recently. Between 1950-1970, the annual death rate due to candidiasis has been on steady rate. And Since then the rate has increased significantly in association with several changes in medical practice, such as more widespread use of therapies that suppress the immune system, indiscriminate use of broad-spectrum antibiotics, the common use of indwelling intravenous devices, and the advent of chronic...