This volume contains the proceedings of the Entretiens de l'Institut International de Philosophie (IIP) held in September 2009 at the University of Coimbra. The chosen subject - 'Cause, Knowledge, and Responsibility' - was sufficiently broad in scope to allow approaches to it from various theoretical points of view. The papers envisage providing input to the intense discussions on these contested topics, addressed by the many references reviewed by the contributors. Contents include: Platonism and the Argument from Causality * Descartes and Virtue Epistemology * On Risk, Knowledge, and...