Michael J. LaMastra wrote this book based on his research while attending Roswell Park Cancer Institute for his first masters degree. While we knew that HPV-associated head and neck cancer was different from tobacco/alcohol related head and neck cancer, we did not know why. The answer was genomic instability. Human Papillomavirus type 16 (HPV-16) has been shown to be an independent etiologic agent, with virus-positive tumors exhibiting better prognoses.This study aimed to determine if there are quantitative and/or qualitative differences in the genomic instability patterns of HPV-16 positive...