When a bus full of tourists infected with a genetically engineered virus stops in a quiet community, the area threatens to become the epicenter for a worldwide outbreak. Two Vista County deputies race to contain the revived dead, stop the spread of the virus, and combat the chaos and anarchy that ensues.

As hordes of infected continue their murderous rampage through the small town of Lost Hills, Vista County Sheriff Deputies, Connor and Matt, continue the battle to rescue their families from the deranged hands of Curtis White. Time is short as they fear he will settle his grudge by adding their families to the mounting number of bodies left in the wake of his destruction. Meanwhile, Connor's brother, Zeke, faces his own obstacles as he attempts to escape Atlanta before the virus unleashed in the Chinese bio-attack infects the entire population, turning people into ravenous, infected monsters....