The present study was undertaken with the objectives to evaluate the specificity of different diagnostic tests in clinical cases of rabies, to evaluate pathomorphological changes in experimentally induced rabies with fixed and Street virus in mice and to determine the expression of proinflammatory cytokines and their relation to clearance of virus from brain tissue in mice. A total of 114 brain samples of rabies were collected from suspected cases and these samples were subjected to Sellers staining, FAT, dRIT and RT-PCR for the diagnosis of rabies. Of these 81 samples were tested positive...