Liver is the first organ to metabolize all foreign compounds and hence it is susceptible to many different diseases. Liver disorders attribute to its exposure to different xenobiotics, among them is the paracetamol drug. Xenobiotics mainly damage the liver by producing reactive oxygen species (ROS). Acetaminophen (paracetamol) is a widely used analgesic and antipyretic drug, it causes hepatotoxicity in experimental animals and humans at high doses. Most of the present drugs have severe side effects. Thus, the current trend in many therapies is the back to nature. Therefore, it is necessary...

Osteoporosis is a socio-economic problem that requiring appropriate management strategies to modulate the bone turnover disorder. Estrogen replacement therapy and bisphosphonate drugs are effective for both prevention and therapy of osteoporosis, but recent findings have shown that their long term administration are not safe. Thereby natural alternative treatments are urgently needed. Therefore, the present study selected Cicer arietinum seed extract as a phytoestrogen source and/or Coelatura aegyptiaca shell powder as a calcium source to evaluate their effectiveness against osteoporosis...

Liver disease is still a worldwide health problem. Unfortunately, conventional or synthetic drugs used in the treatment of liver diseases caused serious side effects. This is one of the reasons for many people world widely, to turn to complementary or alternative medicine.Recently, the natural medical material of animal origin and pharmaceutical preparations on their basis as well as biologically active food supplements are the future medicine for diseases.Therefore,the present study selected Allolobophora caliginosa as natural supplement of animal origin to evaluate its efficacy against...