The effectiveness of irrigation relies on both the mechanical flushing action and the ability of irrigants to dissolve tissue. The flushing action of irrigants helps to remove organic dentinal debris and microorganisms from the canal.The success of endodontic treatment depends on the eradication of microbes from the root canal system and prevention of reinfection. The root canal is shaped with hand and rotary instruments under constant irrigation to remove the inflamed and necrotic tissue, microbes/ biofilms, and other debris from the root canal space. The main goal of instrumentation is to...