This book covers the various approaches of Vilsmeier-Haack reaction and their synthetic applications. The work of the book is devoted to a study of a series of organic reactions which employs Vilsmeier-Haack reaction to synthesize various heterocyclic derivatives. Vilsmeier-Haack reaction is a key step for the conversion of various functional groups to desire group/moiety. Recent advances in the Vilsmeier-Haack reaction is elaborated with their wide range of synthetic applications that may help the researchers for future endeavor in organic synthesis. Improved and modified conditions applied...
This book covers the various approaches of Vilsmeier-Haack reaction and their synthetic applications. The work of the book is devoted to a study of a ...
The present book describes the one pot route for quinoline fused azeto 1,2-a]benzimidazole derivatives, involving condensation of o-phenylenediamine with 2-chloroquinoline-3-aldehydes and subsequent Pd-catalyzed cross coupling of resulting benzimidazole N H with 2-choloroquinoline leading to the formation of four-membered azetidine ring as a key step. Synthesized analogs were further tested for antimicrobial, antimycobacterial and anti-prostate cancer activity to observe the variation in biological activity. The bioassay results revealed that the majority of final analogs exhibited potential...
The present book describes the one pot route for quinoline fused azeto 1,2-a]benzimidazole derivatives, involving condensation of o-phenylenediamine w...
The proposed book gives an outline of the design, synthesis, characterization and various biological activities (antibacterial, antifungal, antituberculosis and anticancer) of novel urea/thiaourea functionalized quinazoline scaffolds. We have developed an efficient technique to introduced Suzuki C-C reaction on quinazoline and urea/thiourea moieties. The antimicrobial activity of synthesized analogs has been carried out against two Gram-positive bacteria, three Gram-negative bacteria and two fungi using paper disc diffusion method and agar streak dilution method. The synthesized analogs were...
The proposed book gives an outline of the design, synthesis, characterization and various biological activities (antibacterial, antifungal, antituberc...
An efficient catalytic system for the synthesis of quinolinyl ureas have been developed using Pd based catalyst system. All these synthesized quinolinyl ureas have adequate pledge as active drug candidates via a novel process. The in vitro biological screening data of the newly synthesized analogs revealed that majority of the compounds have demonstrated noticeable antimicrobial against various panels of microorganisms.
An efficient catalytic system for the synthesis of quinolinyl ureas have been developed using Pd based catalyst system. All these synthesized quinolin...
The book is focusing on novel progress of Pd catalyzed C-N coupling of weak nucleophile: Urea and Amide.Although a number of book dealt with transition metal catalyzed N-arylation of amines (all classes), to date no specific book covering the Palladium catalyzed N-arylation of amide and urea appeared. This book increases the practicality of amidation and ureidation applications through the concise analysis of previous work. This book discusses these developments with regard to substrate scope and the nature of the corresponding catalyst systems. Emphasis will be placed on applications of...
The book is focusing on novel progress of Pd catalyzed C-N coupling of weak nucleophile: Urea and Amide.Although a number of book dealt with transitio...
