DNA triple helices are formed by the binding of a third strand oligomer in the major groove of a Watson -Crick (WC) duplex. Interest in triple-helical nucleic acids-that is, triplex has been stimulated by the recognition of their potential biological roles and genetic applications. Although direct evidence of participation of triplexes in biological processes has not yet been obtained, there are ample data to suggest that triplexes can be involved in regulation of DNA replication, transcription, recombination and development.During DNA triplex formation third oligonucleotide strands binds...