Doctoral Thesis / Dissertation from the year 2014 in the subject Medicine - Biomedical Engineering, Cairo University (Faculty of Science), course: Immunology, language: English, abstract: P. aeruginosa is a gram-negative bacterium that causes a variety of diseases in compromised hosts. Bacterial endotoxins such as LPS are the major outer surface membrane components present in almost all gram-negative bacteria and act as extremely strong stimulators of innate immunity and inflammation of the airway. The present study was undertaken to determine the effect of combined administration of...

Despite effective chemotherapy, fascioliasis remains a major public health problem in developing countries, with at least 17 million active infections, resulting in significant morbidity, late infection detection, and rapid reinfection after treatment. Therefore, alternative control strategies are mandatory. Proteases, myofibrillar proteins, are found only in invertebrates. In the present study, adult fresh Fasciola gigantica (F. gigantica) worms were homogenized; an antigen was purified and used to raise rabbit polyclonal antibodies (pAb). The purified pAb was then used in sandwich ELISA to...