The entire spectrum of vascular disease is examined in this issue of Cardiology Clinics. Topics include carotid artery disease, endovascular interventions for thoracic and abdominal aortic aneurismal disease, critical limb ischemia, contemporary treatment of venous thromboembolic disease, renal artery stenosis, resistant hypertension, advances in peripheral arterial disease revascularization, stroke interventions, medical management of PAD, pre-operatory evaluation of vascular patients.