Asthma is a complex genetic disease, which arises from the interaction of multiple genes and environmental stimuli.These can be mechanically explained by the Epigenetic phenomenon, which consists of the chromatin and its modifications, as well as a covalent modification of cytosines residing at the dinucleotide sequence CG in DNA by methylation. This reaction is catalyzed by a family of DNA methyltransferase enzyme (DNMTs). DNMT1 is one of them which maintained the methylation status during replication and also critical for the development, differencian and regulation of Th1 and Th2 cells as...
Asthma is a complex genetic disease, which arises from the interaction of multiple genes and environmental stimuli.These can be mechanically explained...