Imidazoles have always manifested fascinating biological properties and many of these molecules have been individually elaborated to pharmaceuticals. They represent one of two major classes of antifungal azole derivatives: the imidazole group has contributed significantly to the therapy of both superficial and systemic mycotic infections. Azaheterocycles constitute a very important class of compounds. In particular, pyrimidine derivatives include a large number of natural products, pharmaceuticals, and functional materials. While development of important methodologies for the synthesis of...