Pyrimidine and its derivatives have been studied for over a century due to a variety of important chemical and biological applications. A number of heterocylic compounds fused with pyrimidines are known for their varied biological activities. They have been reported as antibacterial, antiviral and anti-tumor agents etc. In recent years, microwave irradiation using commercial scientific ovens has been rapidly increased for optimization and acceleration of organic synthesis under solvent free conditions. It has been reported for the variety of reactions such as synthesis of heterocycles and...

The importance of derivatives of pyrimidines such as pyrazolo, thiazolo and triazolo pyrimidines as biologically active compounds includes their use as antibacterial, antimicrobial , antibacterial, antihypertensive, antileishmanial, and anticonvulsants agents etc. Microwave assisted organic synthesis has proved to be excellent sophisticated tool for the synthesis of organic compounds. Alkylation reactions and condensation reactions are carried out with the said technique successfully in the present work.The synthesis of pyrazolo, thiazolo & triazolo pyrimidines has been successfully carried...

Quinazoline derivatives are of special importance because of their versatile biological and pharmacological activities especially anti-inflammatory, anticonvulsant, hypnotic, anthelmentic, hypotensive, antibacterial agents etc. Microwave irradiation using scientific ovens has been rapidly increased for the variety of reactions such as synthesis of heterocycles due to reduction in reaction time, improved energy utilization, potential for lower processing temperature and improved product uniformity. Alkylation & condensations are carried out with the said technique successfully in the present...