Cattle industry is drastically affected by the trematode parasite Fasciola gigantica. This work aims to study the humoral and cellular immune responses to different F. gigantica antigens isolated from adult worm E/S product during the parasite invasion. This research is an attempt to find an effective vaccine against the parasite.Two Antigens were isolated and purified from excretory/secretory products as cysteine protease and fatty acids binding proteins (CP and FABP) of the parasite by immunoaffinity chromatography. From this study it was deduced that F. gigantica CP is a relevant candidate...
Cattle industry is drastically affected by the trematode parasite Fasciola gigantica. This work aims to study the humoral and cellular immune response...
Fascioliasis is a disease of human and grass-grazing animals caused by the parasitic worm Fasciola spp; which lives in the bile ducts and cause liver cirrhosis. It is generally agreed that facsioliasis caused heavy economic loss in liverstock throughout the world. Clinically, fascioliasis may be falsely diagnosed asamoebic hepatitis, acute infective hepatitis as well as disorders associated with cirrhosis and primary carcinoma of the liver. Several tests using different fasciolal antigenic preparation, including partially purified antigen and excretory-secretory (ES) products of the adult...
Fascioliasis is a disease of human and grass-grazing animals caused by the parasitic worm Fasciola spp; which lives in the bile ducts and cause liver ...
BSL could be a promising anti-initiation agent in vitro through inhibition of CYP 1A mediated carcinogen metabolism and induction of GST activity as well as GSH level. BSL also possesses anti-inflammatory activity through its capacity to enhance macrophage proliferation rate and its ability to inhibit stimulated NO, TNF- and COX-2 levels. Besides preventing tumor promotion, BSL showed inhibitory activity toward DNA fragmentation and cytotoxic property against Hep-G2 tumor cell line as anti-progression properties. In vivo administration of BSL before and after DEN induction showed inhibitory...
BSL could be a promising anti-initiation agent in vitro through inhibition of CYP 1A mediated carcinogen metabolism and induction of GST activity as w...
The efficacy of rabies vaccine by using adjuvant due to its documented immunostimulatory characteristics. The immune response was measured through measuring cellular immune response using lymphocyte proliferation test, while humoral immune response was traced using two different assays, virus neutralizing antibodies assay ELISA. The study proved the efficacy of Adjuvant candidate for inactivated RABV administrated parenterally.
The efficacy of rabies vaccine by using adjuvant due to its documented immunostimulatory characteristics. The immune response was measured through mea...
The use of parasitic worms-derived cysteine proteases, for serodiagnosis implies that these molecules elicit strong immune responses during natural infection. In conclusion, the efficacy of worm-derived protein in immunodiagnosis and prevention of animal disease is the aim of work. The findings together suggest that parasite total protein may be used as easily available, safe and inexpensive antigens for immunodiagnosis and transmission reduction of animal diseases.
The use of parasitic worms-derived cysteine proteases, for serodiagnosis implies that these molecules elicit strong immune responses during natural in...
