This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was named P-glycoprotein. It elicits resistance to cytotoxic drugs, chiefly in human tumours, within which chemotherapy failure is observed in about 50% of cases. Together with its complex pharmacology, and even a suspected role in Alzheimer's disease, this ABC transporter still eludes a clinical...

Have you been dreaming of that mind-blowing solo but don't know where to start?

Do you have a guitar Idol you wish to play like, but your fingers just cant keep up?

The High Intensity Guitar Technique series is the ultimate guide for guitarists wishing to expand their technical ability. The series aims to give a guitar player that feels bogged down, the skills they need in order to be able to play any riff, run, solo or lick they should wish to, from any genre of music. This first book in the...