Various factors have been reported which contribute to the failure of root canal treatment. The presence of persistent intraradicular infection due to surviving microorganisms in the root canal is one of them. The positive correlation between bacteria and endodontic disease has been established. Microbial control within pulpal tissue and root canal space is a prerequisite for the prevention and treatment of pulpal and periapical breakdown. Therefore, during root canal treatment it is very important to control microbial agents by biomechanical procedures, which can be carried out successfully...

"The best & the most beautiful things in the world cannot be seen or even touched. They must be felt with the heart. - Hellen Keller." Special and medically compromised patients present a unique population that challenges the dentist's skills and knowledge. The handicapped patients differ from normal patients with regard to professional relationship between patient and the dentist. Therefore with adequate training and understanding of the various medical complications and handicapping conditions and with adequate alteration in the dentist's treatment protocol these patients can be managed...