Pyrimidine is a well known heterocyclic compound, which has been subjected to a large variety of structural modification in order to synthesize derivatives with different biological properties. Pyrimidine derivatives have been reported to possess a broad spectrum of pharmacological properties. Pyrimidine is the most important member of all the diazines as this ring system occurs widely in living organisms. Purines, uric acid, barbituric acid and some anti-malarial and anti-bacterial agents also contain the pyrimidine ring.

Oxadiazole derivatives constitute an important family of heterocyclic compounds. Since many of them exhibit a remarkable biological activity and find wide usage as dyes, photosensitive electrical materials, polymer precursors & stabilizers. Particularly, the 2-aryl-5-substituted-1,3,4-oxadiazoles have been reported to show antibacterial, antifungal, analgesic, anti-inflammatory and hypoglycemic activities.

The substituted chalcone and isoxazole are considered to be important synthons due to their versatility towards chemical transformations to useful synthetic intermediates as well as various biological activities. The book focuses on main aspects of chemical reaction, mechanism and applications of synthetic utility. The content is explained in an easy and simple language. It will be a good source of information about fundamental knowledge of organic synthesis of chalcones and isoxazoles as well as reaction path with mechanism to students at undergraduate level, post Graduate level, researchers...

1,2,4-Triazoles have proved to be most useful framework for biological activities among nitrogen containing five membered heterocycles. 4-Aryltriazole derivatives have been found to be potent drug which possess a wide spectrum of biological activity. Different types of 1,2,4-triazole derivatives shows variety of pharmacological activities such as antidepressant, anti-inflammatory etc. Considering the increasing importance of compounds bearing 1,2,4-triazole nucleus, Its construction has attracted considerable attention of researchers. The book focuses on main aspects of chemical reaction,...

The work to be presented in this book entitled "1,3,4-Thiadiazoles" is divided into 8 units. This book reports the strategic designing, synthesis and biological screening of title compounds wherein the biologically active [1,2,4]triazolo[3,4-b][1,3,4]thiadiazol scaffold is linked to potent chroman moiety. The present communication reports the strategic designing, synthesis, characterization and antimicrobial screening of novel 3-(6-Fluorochroman-2-yl)-6- aryl-[1,2,4] triazolo [3,4-b][1,3,4]thiadiazoles. Unit-1 deals with the General introduction of our research work, Unit-2 covers the...