The entire pharma industry is faced with the confront of growing productivity and novelty. The major hurdles are the increasing costs of research and development and a simultaneous stagnating number of new chemical entities. Taking in view of the applicability of heterocyclic compounds, in the present work several entities containing heterocyclic nucleus have been selected.Combinatorial and parallel chemistry are powerful tools for medicinal chemists in drug detection programs. It has expectant chemists to work out synthetic strategies and approaches that can be used for the construction of...

Generally pyrimidine derivatives such as 2-hydroxy-substitutedpyrimidine, 2-mercapto-substituted-pyrimidine and 2-amino-substituted pyrimidine are studied. Pyrimidines have been isolated from the nucleic acid hydrolysates. Pyrimidines are among those molecules that make life possible, have been some of the building blocks of DNA and RNA. Several analogues of pyrimidines have been used as compounds that interfere with the synthesis and functioning of nucleic acids e.g. fluorouracil, which has been used in cancer treatment. Modifications in the base, sugar and phosphate moieties of...

The present research work deals with the quality of underground well/tube well water and inter-relationship within the properties of well/tube well water samples. Representative water sample were collected and analyzed using the standard procedures of water analysis. Following the methods listed by Richards (1954), the accuracy and precision of the analyses were checked up. Statistical Study Of Water Analysis done by Dr. Kamlesh Patel.