As on oral administration, Raloxifene Hydrochloride undergoes extensive first pass metabolism resulting in poor bioavailability. The Objective of the present study was to prepare a matrix patch of Raloxifene Hydrochloride to increase its bioavailability. The main aim of the work is to provide a safe, simple and alternative route of administration for the prevention of osteoporosis in post-menopausal women. This book gives insights into the innovative world of non invasive transdermal drug delivery. This compilation of work explains the preformualtion, formulation considerations, methodologies...
As on oral administration, Raloxifene Hydrochloride undergoes extensive first pass metabolism resulting in poor bioavailability. The Objective of the ...
Most of herbal formulations have lacking of preformulational and post formulational studies. Thus, an attempt was made to performed the preformulation and post formulation characteristics for senna leaf powder and calcium sennoside. The conventional tablet of senna leaf powder and calcium sennoside may release a significant amount of drug in the physiological environment of stomach before reaching at the site of action. Hence, enteric coated tablet of calcium sennoside and senna leaf powder was prepared using cellulose acetate phthalate for averting the initial loss of 5-8% sennoside in...
Most of herbal formulations have lacking of preformulational and post formulational studies. Thus, an attempt was made to performed the preformulation...