This review has been aimed at the treatment of rheumatoid arthritis and their significance. Rheumatoid arthritis is the most important systemic disease. The current review information has been found to reveal both remarkable active medicine and a variety of valuable practical applications. An interest in the exploration of this medicine has undoubtedly been growing due to their proven utility as attractive lead structures for the design of novel agents with a mechanism of action that sometimes differs from that of clinically authorized current antirheumatic drugs. Therefore, in the present...

Tuberculosis remains primary cause of comparatively high mortality worldwide. The statistics highlighted that three million people worldwide die annually from complication of TB and there are estimated 8 million of new cases each year, and today more people die from tuberculosis than ever before. In recent history, however, poor compliance with the prolonged and complicated chemotherapeutic regimens currently used to treat the disease, in conjunction with the advent of the AIDS epidemic and the increased mobility of human populations, has led to the emergence of numerous multidrug resistant...