This textbook will help a lot of researchers in the academia on procedures involved in quality control of drugs. It is a must read. In this edition, we evaluate two drugs- Ficus abutilifolia (Moraceae) and Annona senegalensis (Annonaceae). These plants have been used for treating various ailments in Nigeria especially in the management of typhoid fever, malaria, sexually transmitted infections such as syphilis, gonorrhea, staphylococcus and others. Quality evaluation of crude drugs will help to prevent adulteration of the product.