This book provides overview of immunoadjuvants in vaccines formulations that play an important role in the induction of effective/appropriate immune responses to vaccine component(s). Wide arrays of compounds have been studied with antigens that are poorly immunogenic over the past several years and vast majority failed due to an unacceptability safety profile. Alum is a strong inducer of humoral responses to vaccine antigens with a skew towards Th2 type of responses and has been effectively used with tetanus, diphtheria, and pertussis. However, alum does not seem to be appropriate choice as...