This monograph reports regional cancer mortality rates among American Indians and Alaska Natives (AI/ANs) within areas served by the U.S. Department of Health and Human Services (DHHS), Indian Health Service (IHS). These areas are comprised of certain counties found within 35 states. AI/ANs residing in these counties represent about 56% of the total AI/AN bridged single-race population in the United States. We present the cancer mortality rates for 1999-2003 for the principal cancer types and compare them with the general U.S. population rates during the same period. We also present the...