A variety of novel pyrimidine, thiosemicarbazide and semicarbazide derivatives have been reviewed. Based on brief review of compounds will be subject to in vitro assessment for their antitumor and antimicrobial activities, and compounds are believed to be the most active members in this study. The tested compounds exhibit excellent anticancer and antimicrobial activities against both clinical cancer isolates and microbial pathogenic strains.

Development in biological evaluation of heterocyclic molecules has undergone manifold changes and the advancement in molecular biology has eased the design of new molecules based on their mechanism of action. Proposed work is based upon the development of newer analogues of benzothiazoles followed by their biological evaluation. Benzothiazoles have been reported with good biological activities ranging from antiparasitic, anti-inflammatory, antitumour, p56lck inhibition, immunosuppressive antitubercular activity etc. The derivatives of benzothiazoles have been developed very recently,...