Homoisoflavonoids (3-benzylidenechroman-4-ones) are related to flavonoids and occur as natural products and exhibit various biological activities. Because of these properties, organic chemists are very interesting to homoisoflavonoids. The present study was designed to examine the interactions of four synthetic homoisoflavonoids (BMC, BPC, HBC and HBMC) that exhibit antioxidant, antifungal and antiviral activities, with calf-thymus DNA and RNA in aqueous solution at physiological conditions, using constant DNA and RNA concentration and various homoisoflavonoids/polynucleotide (phosphate)...