Due to larynx vital role in phonation, respiration and deglutition the study main purpose was to preserve its functions and to assess the therapeutic option for bicordal-commissure laryngeal glottic cancer. Histopathological, histochemical and immunohistochemical morphologic exam represents an essential stage in diagnosis, resection margins and prognosis evaluation. A multimodal approach of bicordal-commissure glottic carcinoma from the clinic to the lab and beyond is necessary because it represents a complex disease due to the evaluation, diagnosis, staging, treatment indications and...