Predlagaemaya Vashemu vnimaniyu kniga vklyuchaet v sebya osnovnye printsipy organizatsii patomorfologicheskoy diagnostiki raka molochnoy zhelezy, obespechenie v gistologicheskoy laboratorii usloviy obespecheniya kachestva vypolnyaemykh issledovaniy, organizatsiya sistemy peresmotra (referensa) immunogistokhimicheskikh issledovaniy, vypolnyaemykh v laboratorii pervogo prosmotra. Oboznacheny osnovnye trebovaniya dlya vypolneniya immunogistokhimicheskikh issledovaniy v laboratorii pervogo prosmotra, regional'noy referens-laboratorii, tsentral'noy referens-laboratorii. Propisany osnovnye zadachi...

Predlagaemaya Vashemu vnimaniyu kniga vklyuchaet dannye po immunogistokhimicheskoy kharakteristike retseptornogo apparata kletok infil'trativnoy kartsinomy molochnoy zhelezy (Estrogen receptor, Progesterone receptor, C-erb2) i ustanavlivaet ikh svyaz' s urovnem proliferatsii kletok opukholi (po stepeni ekspressii Ki67). Razobrany osnovnye signal'nye vnutrikletochnye puti, zadeystvovannye v etom protsesse. Issledovanie podtipov infil'trativnykh kartsinom molochnoy zhelezy po gruppam proliferatsii osushchestvleno otdel'no polozhitel'nykh i otritsatel'nykh po ekspressii retseptorov i C-erb2...

V predstavlennom issledovanii nauchno obosnovano, chto effektivnaya lekarstvennaya profilaktika raka molochnoy zhelezy privodit k snizheniyu indeksa proliferativnoy aktivnosti. Na osnovanii sravnitelnogo analiza metodov lekarstvennoy i kombinirovannoy profilaktiki raka molochnoy zhelezy s ispolzovaniem slozhno-modulirovannogo nizkochastotnogo elektromagnitnogo polya, polucheny novye dannye o tom, chto klinicheskie, instrumentalnye i standartnye metody morfologicheskogo issledovaniya nedostatochno kharakterizuyut dinamiku ochagovoy formy fibrozno-kistoznoy mastopatii. Vpervye dokazano, chto...

V nastoyashchey monografii obsuzhdayutsya nekotorye pravovye voprosy, voznikayushchie pri vnedrenii v uchrezhdeniya prakticheskogo zdravookhraneniya v Rossiyskoy Federatsii metodov regenerativnoy meditsiny, osnovu kotoroy sostavlyayut biomeditsinskie kletochnye tekhnologii. Eto obuslovleno v svoyu ochered' poyavleniem novykh ob"ektov - kletochnykh i tkane-inzhenernykh produktov, obrashchenie kotorykh ne ukladyvaetsya v uzhe sushchestvuyushchie reglamenty, otnosyashchiesya k lekarstvennym sredstvam i meditsinskim izdeliyam. Aktual'nost' i osobennosti dannoy raboty svyazany s...

V monografii predstavlen 25 letniy opyt v diagnostike i lechenii predrakovykh zabolevaniy molochnykh zhelez v onko-mammologicheskoy klinike Ural'skogo gosudarstvennogo meditsinskogo universiteta. Pokazana vozmozhnost' putem postanovki kompleksa aktivnykh meropriyatiy, vklyuchayushchikh ratsional'nyy skrining, organizatsiyu samoobsledovaniya molochnykh zhelez, lechenie predrakovykh sostoyaniy, dobit'sya snizheniya smertnosti ot raka molochnoy zhelezy v kontroliruemom kontingente naseleniya. Sovershenstvovanie metodov diagnostiki i organizatsionnykh form vyyavleniya predrakovykh zabolevaniy i...