Sol-gel derived metal oxide nanostructures based biosensors have shown potential application in various fields including mainly environmental and biological screening/monitoring. Composite film of CeO2-SiO2 has been fabricated using sol-gel technique to prepare enzymatic and DNA biosensor for the detection of triglyceride and cypermethrin, respectively. Lipase (Lip) and double stranded calfthymus (dsCT) was immobilized via physiosorption for the biosensing of respected analyte. The electrical response studies of Lip/CeO2-SiO2/ITO carried out using CV reveals linearity from 50 to 400 mg/dL...