Connexins constitute a large family of transmembrane proteins that allow intercellular communication,transfer of ions and small signalling molecules between cells.Gap Junctions are critically important in regulating cell apoptosis and normal cell growth and differentiation.The Cx43 gene sequence remains relatively conserved among species,indicating its presence is very important for survival.Connexin 43 protein plays an important role in normal mammogenesis, lactogenesis and involution. Several studies have shown that downregulation of Connexin 43 protein is involved in primary tumor...
Connexins constitute a large family of transmembrane proteins that allow intercellular communication,transfer of ions and small signalling molecules...
