Buccal route of drug delivery is one among novel drug delivery systems where there is high blood perfusion rate that will enable good bioavailability without wasting drug due to first pass metabolism as in case with oral route and making whole dose of drug available for absorption into systemic circulation, hence improving the bioavailability. The current research uses the advantage of BDDS and aims at delivering an anti-diabetic drug (Metformin HCl) in controlled manner using different biodegradable polymer combinations and achieved expected results of high bioavailability, controlled and...