Bacteriocins are regarded as the next generation of antibiotics due to their narrow-spectrum bactericidal activities. Lactic Acid Bacteria (LAB) are considered as Generally Recognized as Safe (GRAS) microorganisms that have been used in the processing of fermented food for centuries. Many lactic acid bacteria produce broad-spectrum bacteriocins, some of which could provide valuable alternatives to traditional therapeutic antibiotics for the treatment of infectious diseases. Lactobacillus sp. Y18 isolated from the Egyptian commercial yoghurt showed the highest antimicrobial activity (12800...