advanced metastatic disease of solid tumors, dictates that each tumor mass, indeed each individual metastasis, will have a unique antigen and cytokine environment and hence unique response to immune modu lation. A differential response to immunotherapy is thus inevitable. 4. Many of the human trials described are not randomized and report survival or response against historical controls. Most tumors described are immunogenic human tumors: renal cell cancer and melanoma are most common. In order to avoid the well-described inter-patient vari ation and rare incidence of spontaneous response...
advanced metastatic disease of solid tumors, dictates that each tumor mass, indeed each individual metastasis, will have a unique antigen and cytokine...
The Children's Crusade was possibly the most extraordinary event in the history of the crusades. The first modern study in English of this popular crusade sheds new light on its history and offers new perspectives on its supposedly dismal outcome. Its richly re-imagined history and mythistory is explored from the thirteenth century to present day.
The Children's Crusade was possibly the most extraordinary event in the history of the crusades. The first modern study in English of this popular cru...
