While human lifespan has dramatically increased over the years, the focus is shifting to healthspan, the duration of ones lifespan in which one is fit and healthy. Longer lifespan has created new challenges for biomedical sciences and there is an urgent need to better understand factors supporting healthy aging. Growing evidence suggests that biological (circadian) clocks are functionally linked to aging, and age-related pathologies including neurodegenerative diseases. Research conducted in this dissertation supports the neuroprotective effects of clocks, and provides a comprehensive picture...
While human lifespan has dramatically increased over the years, the focus is shifting to healthspan, the duration of ones lifespan in which one is fit...