Alcoholism is such a common condition that almost every clinician is confronted with its complications, of which one of the most common is Alcohol withdrawal syndrome. Alcohol withdrawal occur because alcohol is a central nervous system depressant. Chronic ethanol use induces an insensitivity to GABA such that more inhibitor is required to maintain a constant inhibitory tone. Glutamate is one of the major excitatory amino acids. Ethanol inhibits glutamate induced excitation. Adaption occurs by increasing sensitivity to glutamate in an attempt to maintain a normal state of arousal. Only the...
Alcoholism is such a common condition that almost every clinician is confronted with its complications, of which one of the most common is Alcohol wit...
