Knowledge of three dimensional structures of protein targets emerging from genomic data has the potential to accelerate the drug discovery. Computer assisted drug development (CADD) is based on the integration of mathematical modeling and simulation. This methodology provides a knowledge based decision tool on the development strategies based on the evolution of potential risk on drug safety and the definition of experimental design of new trails with expected power and probability of success. Modeling of new drug compound structures for heart disorders and tuberculosis are discussed in this...
Knowledge of three dimensional structures of protein targets emerging from genomic data has the potential to accelerate the drug discovery. Computer a...