Polymorphisms within the 2-adrenergic receptor(B2ADR) gene have been repeatedly linked to hypertension. Among the B2ADR polymorphisms detected, Arg16Gly and Gln27Glu codons are considered the two most important variations. The amino acid substitution at these codons may lead to abnormal regulation of B2ADR activity. The aim of the present study was to assess the association between B2ADR polymorphisms and hypertension. This case-control study consisted of 100 unrelated subjects (50 hypertensive and 50 matched normal controls). Arg16Gly and the Gln27Glu polymorphisms were analyzed by...