In this manuscript, I have planned the acquisition of a single lead ECG signal and explored the important steps and hurdles while digitizing and recording the ECG signal. ECG signal is given to a band-pass filter, then digitized and sent to the computer, using serial communication. MATLAB is used to store this data as an array file and attenuation of noise occurs using mine own designed algorithms. Then calculate the various intervals and identify various diseases quite accurately and preciously.