Maintaining performance guarantee of applications running in Grid environment has always been a demanding research area. Grid provides scalable, secure pool of virtual high-end resources. This work proposes an agent-based integrated framework for automated performance analysis and tuning of compute intensive applications running in computational Grid environment. Objective of this work is to design and implement the framework with two definite components - the first one is an automated performance analysis system that gathers performance-monitoring data and on the basis of this data detects...