Bladder cancer is a global health issue. In the endemic areas of Egypt, schistosomiasis is a leading cause of bladder cancer. Prognostic indicators are required to further identify which tumor should be treated aggressively early on, in order to improve surveillance. The Fas-Fas Ligand (Fas-FasL) system has been recognized as a major pathway for the induction of apoptosis in cells and tissues. Fas-mediated apoptosis is deeply involved in cancer cell death, brought about by the immune system. The interaction of Fas and Fas Ligand contributes to cytotoxic T-lymphocyte and natural killer-cell...