Quality, safety and effectiveness must be built into the product. This requires careful attention to a number of factors such as the selection of quality materials/components, product and process design, control of processes, in-process control, and end-product testing. Due to the complexity of the drug products, routine end-product testing alone is not sufficient due to several reasons. Furthermore, quality cannot be tested into the finished drug product but rather be built in the manufacturing processes and these processes should be controlled in order that the finished product meets all...

Nanoparticles hold tremendous potential as an effective drug delivery system. In this overview we discussed recent developments in nanotechnology for drug delivery. To overcome the problems of gene and drug delivery, nanotechnology has gained interest in recent years. Nanosystems with different compositions and biological properties have been extensively investigated for drug and gene delivery applications. To achieve efficient drug delivery it is important to understand the interactions of nanomaterials with the biological environment, targeting cell-surface receptors, drug release, multiple...

Novel drug delivery systems constitute the main stay of pharmaceutical research and development. Various novel drug delivery systems exists in the pharmaceuticals and one of such delivery system is nanoparticles. Nanoparticles are monolithic systems in which the drug is adsorbed, dissolved, or dispersed throughout the matrix. There are various forms of nanoparticles, out of which a newer and novel system is buckyballs. Buckyball is a member of a class of carbon structures called fullerenes. Hence they are also known as Buckminsterfullerene or fullerene. They are discovered by British...

The aim of present study was to formulate and evaluate the mouth dissolving tablets of flurbiprofen using various superdisintegrants for rapid disintegration, to improve patient compliance and to obtain disintegration time

In the present work, an attempt was made to formulate buccoadhesive gel for the treatment of oral submucousal fibrosis. The aim was to assess the influence of type and concentration of gelling agents: Carbopol 934p and sodium carboxy methyl cellulose on the quality attributes of buccoadhesive gel. All the proposed five buccoadhesive gel formulations were prepared. The prepared gels were evaluated and In-vitro release of metronidazole and lycopene at 240 min from buccoadhesive gel determined.The release of lycopene not satisfactory from optimized gel formulation, to increase the release of...

A generic drug (generic drugs, short: generics) is a drug which is produced and distributed without patent protection. The generic drug may still have a patent on the formulation but not on the active ingredient. Based on clinical, pharmacokinetic and statistical data obtained from 18 subjects normal, adult, human subjects under fasting conditions, it was concluded that both the formulations were well tolerated following a single dose administration of the investigational product and test formulation was found to be bioequivalent to the reference formulation the 90% confidence intervals for...

The theme of the seminar chosen was "Recent Advances in Pharmaceutical Education and Research." The objectives of the seminar were to explore the basic, technical and innovative trends in formulation various novel, controlled and targeted drug dosage forms, to improve knowledge and share the prospective ideas in the formulation design and to articulate a compelling vision of future pharmacy by experts and eminent personalities. this seminar also emphasized to encourage the pharmacy students to participate and presented papers on current edge happening in pharmaceutical education and research...

Forced degradation studies are used to facilitate the development of analytical methodology, to gain a better understanding of active pharmaceutical ingredient (API) and drug product (DP) stability and to provide information about degradation pathways and degradation products.The impurity profiling of the pharmaceuticals is of increasing importance as drug safety receives more and more attention from the public and from the media.LC‐PDA method enables simple, accurate, reproducible and fast quantitative analysis of telmisartan in presence of degradation products. The method has been...