This book was written to have an idea about prostate specific antigen and its role in diagnosis of prostate cancer which is a common cancer in men.and one of the main leading cancer death allover the world. Prostate cancer is one of the treatable cancers, if diagnosed early. Prostate specific antigen is one of ideal tumor markers for early diagnosis motoring prostate cancer, although it is not specific, but the isoforms of this markers are now used to increase the diagnostic utility of this marker.