The field of data mining has made significant and far-reaching advances over the past three decades.Because of its potential power for solving complex problems, data mining has been successfully applied to diverse areas such as business, engineering, social media, and biological science. Many of these applications search for patterns in complex structural information. In biomedicine for example, modeling complex biological systems requires linking knowledge across many levels of science, from genes to disease. Further, the data characteristics of the problems have also grown from static to...