Drug/drug interaction is a situation in which a drug, could affect the activity of another drug, i.e. the effects of the drug are increased or decreased, or produces a new effect that neither of them produces on its own. Thereby often the efficacy or toxicity of a medication is changed. Drug/drug interactions could be attributed into pharmacokinetic or pharmacodynamic interaction. Pharmacokinetic interaction: the drug concentration against time curve in the body is modified. Pharmacokinetic interactions can be based on pharmacokinetic parameters of a drug (absorption, distribution,...