N-Arylhydroxamic acids are drug like molecules. Biological activity always depends upon physico-chemical property namely lipophilicity, which has direct impact on the potency of the molecule. Partition coefficient is a measure of how well a substance partitions between a lipid and water.The partition coefficient has a strong influence on ADME properties of molecules. Both of these parameters are important factor in QSAR.
N-Arylhydroxamic acids are drug like molecules. Biological activity always depends upon physico-chemical property namely lipophilicity, which has dire...
Oral health is an integral part of general health. An improvement in the oral health may play an integral role in improving the general health, adequate instructions in proper care of the teeth and oral tissues is thus essential. It is the responsibility of the health system to provide proper information about maintenance of oral health and available health facilities for general and oral health. In turn the community should use these facilities for their general and oral health betterment. This community is neglected like the old age people by the society and profession. Even though new...
Oral health is an integral part of general health. An improvement in the oral health may play an integral role in improving the general health, adequa...
Hydrophobic character, logP is a physico-chemical property of solute. Knowledge of this hydrophobic character plays an important role to decide the solutes' ability to interface with biochemical systems. It is the measure of the ease with which drug penetrate membranes and bind to lipophilic surface. N-arylbenzohydroxamic acids is drug like molecules it act as anticancer, antiviral, antibacterial etc. and their hydrophobic nature play important role in drug development.
Hydrophobic character, logP is a physico-chemical property of solute. Knowledge of this hydrophobic character plays an important role to decide the so...