Thalassaemias are a group of genetic disorders of haemoglobin synthesis, resulting from a reduced rate of production of one or more of the globin chains of haemoglobin. They are divided into different types according to the polypeptide chains affected; the most common types are thalassaemia and thalassaemia. -thalassaemia associated with total absence or reduced -globin chains and mostly results from point mutations in the coding (exon) or non coding (intron) segments of the globin gene. Most thalassaemias are inherited as mendelian recessive fashion. The thalassaemias are the most important...