Platelet flow cytometry is an emerging tool in diagnostic and therapeutic hematology. It is eminently suited to assess the expression of platelet surface receptors both qualitatively as well as quantitatively. It can thus serve as a useful parameter for in vivo expression of platelet activation and thus fore-warn the risk of thromboembolism which is inherent in patients with untreated type 2 diabetes mellitus. This technique can also be used to study and compare the effect of various antiplatelet drugs on the level of platelet activation and to establish any dose-effect relationship of these...

Soluble transferrin receptors determination is a promising new diagnostic tool for early detection of iron deficiency and also for differentiating iron deficiency anemia from other causes of microcytic and hypochromic anemias. Purpose of this study was to establish the reference range for sTfR in Pakistani population and also to evaluate the role of sTfR as a differentiating marker in the diagnosis of hypochromic and microcytic anemias. Iron deficiency anemia had the highest level of sTfR as compared to normal controls. Anemia of chronic disorders had normal levels of sTfR except in malaria....