Infectious diseases remain as a major world health problem due to the rapid development of resistance to the existing antimicrobial drugs. The spread of resistance among Gram-positive and Gram-negative bacteria as well as fungal pathogens, correlated with increasing limitation in the availability of therapeutic options represent a growing challenge for the development of new antimicrobials. The purpose of this book is to present an updated perspective upon the use of thiourea derivatives as antimicrobial agents, as well as the combination with nanoparticles for enhancing their antimicrobial...

Since amplified bacterial resistance is becoming a concerning phenomenon, especially due to an increase in the reported complications, specialized medical devices that reduce infection rates are a leading and crucial medical research field. Going forward, the current book addresses one of these possibilities by describing one method of optimizing medical devices by modifying them with nanostructured surfaces that prevent the development of adherent bacterial biofilms. Prepared by Matrix Assisted Pulsed Laser Evaporation technique, thin coatings based on silver nanoparticles with a crystalline...

Among all different types of nanoparticles used in nanomedicine, gold nanoparticles (GNPs) are the most investigated, because of their exceptional biocompatibility, unique optical properties and tremendous potential for various treatments that require a personalized approach. In this book, we analyzed various classical and green synthesis methods of GNPs that allow the control of shape, size and physical properties of these nanoparticles. Since non-toxic GNPs are a prerequisite for many biomedical applications, an integrated approach of biodistribution and cytotoxicity of GNPs as well as...