Acute pharyngitis is a common illness in children and adults. Its etiology includes a wide variety of microbial agents. Group A Streptococci (GAS) are the most frequently isolated pathogens in acute pharyngotonsilitis cases in school-aged children. In children, approximately 20% of pharyngitis cases are caused by GAS.15 Streptococcal sore throat is one of the most common bacterial infections of childhood. GAS are responsible for the great majority of such infections and frequently colonize in the throat of an asymptomatic person.GAS consists of a single species, Streptococcus pyogenes. Within...