A variety of pharmacological activities have been exhibited by 2,3-disubstituted 1,8-naphthyridines. For example, 2-amino-1,8-naphthyridine-3-carboxamide is well known for its diuretic property. Further, there has been growing interest in screening the above compounds for their potent antibacterial and antifungal properties. Therefore, the synthesis of 1,8-naphthyridine derivatives has become a continuous interest to synthetic organic chemists. Hence it was felt worthwhile to take up the synthesis of hitherto unreported 2,3-disubstituted 1,8-naphthyridines. Interaction of...

Schiff bases occupy a pride place both in organic and inorganic chemistry, as they have wide applications in many biological aspects. Metal complexes of Schiff bases have occupied a central role in the development of coordination chemistry. Schiff base transition metal complexes are one of the most adaptable and thoroughly studied systems. Isoxazoles are biologically active and have considerable medicinal value. A wide range of biological activities of Isoxazole derivatives include pharmacological properties such as hypoglycemic, antiinflammatory, antibacterial, anticancer and also...